| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 20/02/25 18:45 | Olimpija Ljubljana | FK Borac | 0:0 |
| 20/02/25 18:45 | Pafos FC | Omonia Nicosia | 2:1 |
| 20/02/25 18:45 | 1. FC Heidenheim 1846 | FC Copenhague | 1:3t.pro. |
| 20/02/25 18:45 | Real Betis Balompié | KAA Gent | 0:1 |
| 20/02/25 21:00 | Shamrock Rovers | Molde FK | 4:6pen. |
| 20/02/25 21:00 | Panathinaikos Athenas | Vikingur Reykjavik | 2:0 |
| 20/02/25 21:00 | APOEL Nicosia | NK Celje | 0:2 |
| 20/02/25 21:00 | Jagiellonia Bialystok | TSC Backa Topola | 3:1 |